Iridium-catalyzed regio- and enantioselective allylic substitution of silyl dienolates derived from dioxinones.
نویسندگان
چکیده
Reported herein is the iridium-catalyzed regio- and enantioselective allylic substitution reactions of unstabilized silyl dienolates derived from dioxinones. Asymmetric allylic substitution of a variety of allylic trichloroethyl carbonates with these silyl dienolates gave γ-allylated products selectively in 60-84% yield and 90-98% ee.
منابع مشابه
Iridium-catalyzed enantioselective allylation of silyl enol ethers derived from ketones and α,β-unsaturated ketones.
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عنوان ژورنال:
- Angewandte Chemie
دوره 53 45 شماره
صفحات -
تاریخ انتشار 2014